Journal
TUMOR BIOLOGY
Volume 31, Issue 4, Pages 243-253Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1007/s13277-010-0023-y
Keywords
Cancer stem cells; Challenge; Strategy
Categories
Funding
- Science Foundation of Southeast University [9223001446]
- National Natural Science Foundation of China [90406023]
- 973 Program of China [2006CB933206]
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The hypothesis of cancer stem cells (CSCs) is receiving increasing interest and has become the subject of considerable debate among cancer researchers. Recent rapid progress in CSC research has encountered increasing difficulties and challenges. Understanding the biologic characteristic of CSCs is crucial to start with better identification and diagnosis based on CSC markers and eventually targeting to CSCs will undoubtedly result in improved prevention and treatment of many types of CSCs. We discuss here some of the approaching strategies that include establishing special methods of identifying CSCs and targeting therapies of CSCs.
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