4.3 Article

Pathotyping of a Newcastle disease virus isolated from peacock (Pavo cristatus)

Journal

TROPICAL ANIMAL HEALTH AND PRODUCTION
Volume 42, Issue 3, Pages 415-419

Publisher

SPRINGER
DOI: 10.1007/s11250-009-9436-2

Keywords

Fusion protein cleavage site; Newcastle disease virus; Pathotyping; Peacock (Pavo cristatus)

Funding

  1. Indian Council of Agricultural Research, Government of India, New Delhi

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This report describes Newcastle disease in peacock and the isolation and characterization of the virus. The virus had an intracerbral pathogenicity index of 1.71 and mean death time of 47 h. The isolate had multiple basic amino acids at the fusion protein cleavage site sequence ((110)GGRRQRRFIG(119)) with a phenylalanine at residue 117. Biological and molecular characterization revealed that the virus is velogenic. Phylogenetic analysis placed the isolate in genotype II.

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