Journal
TRENDS IN PARASITOLOGY
Volume 27, Issue 1, Pages 31-39Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2010.06.016
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Funding
- European Commission
- Leiden University Medical Center (LUMC, The Netherlands)
- Netherlands Organization for Scientific Research (ZonMw) [9120_6135]
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The RMgm database, www.pberghei.eu, is a web-based, manually curated, repository containing information on genetically modified rodent-malaria parasites. It provides easy and rapid access to information on the genotype and phenotype of mutant and reporter parasites. The database also contains information on unpublished mutants without a clear phenotype and negative trials to disrupt genes. Information can be searched using pre-defined key features, such as phenotype, life-cycle stage, gene model, gene-tags and mutations. The information relating to the mutants is reciprocally linked to PlasmoDB and GeneDB. Access to mutant-parasite information, and gene function/ontology inferred from mutant phenotypes provides a timely resource aimed at enhancing research into Plasmodium gene function and (systems) biology.
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