Journal
TRENDS IN PARASITOLOGY
Volume 26, Issue 8, Pages 373-375Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2010.05.006
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Funding
- Foundation for the National Institutes of Health through the Grand Challenges in Global Health Initiative of the Bill and Melinda Gates Foundation
- National Health and Medical Research Council, Australia
- Queensland Government
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Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.
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