Journal
TRENDS IN PARASITOLOGY
Volume 25, Issue 2, Pages 85-92Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2008.11.007
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Funding
- DFID
- International Fund for Agricultural Development
- FAO
- Wellcome Trust
- Netherlands Government
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The infection-and-treatment method (ITM) for immunization of cattle against East Coast fever has historically been used only on a limited scale because of logistical and policy constraints. Recent large-scale deployment among pastoralists in Tanzania has stimulated demand. Concurrently, a suite of molecular tools, developed from the Theileria parva genome, has enabled improved quality control of the immunizing stabilate and post-immunization monitoring of the efficacy and biological impact of ITM in the field. This article outlines the current status of ITM immunization in the field, with associated developments in the molecular epidemiology of T. parva.
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