Journal
TRENDS IN NEUROSCIENCES
Volume 41, Issue 11, Pages 772-774Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tins.2018.07.009
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Funding
- NIH [R01NS083898, R01NS103484, R01MH113349]
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How are synaptic vesicles tied together in a nerve terminal? A recent study by Milovanovic and colleagues offers a new mechanism for this old and important problem: synapsin proteins establish a liquid phase that clusters vesicles. Liquid-liquid phase separation provides a fluid-like state that accommodates the dynamic demands of presynaptic vesicle traffic.
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