Journal
TRENDS IN NEUROSCIENCES
Volume 32, Issue 2, Pages 69-72Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tins.2008.11.002
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Funding
- NIMH NIH HHS [1U24MH081810] Funding Source: Medline
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Although autism and schizophrenia are considered to be distinct neuropsychiatric developmental disorders, recent studies indicate that they share genetic factors. The same chromosomal rearrangements and several single genes have emerged as genetic risks in both disorders. One such gene is contactin-associated protein-2 (CNTNAP2). These findings raise the possibility that these neuropsychiatric disorders share pathogenic mechanisms and that similar defects in biological pathways of brain development might underlie the phenotypic spectrum of these disorders.
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