4.6 Editorial Material

Exploring the endocrine manifestations of DICER1 mutations

Journal

TRENDS IN MOLECULAR MEDICINE
Volume 18, Issue 9, Pages 503-505

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.molmed.2012.07.003

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The discovery of each new cancer susceptibility gene answers one set of questions but poses many more. In this article, we outline a recent example: a new cancer syndrome caused by germline mutations in DICER1, responsible for microRNA processing. In particular, we discuss the endocrine manifestations of mutations in this crucial gene.

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