Journal
TRENDS IN MOLECULAR MEDICINE
Volume 14, Issue 10, Pages 450-460Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.molmed.2008.08.003
Keywords
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Funding
- Manitoba Health Research Council (MHRC)
- Natural Science and Engineering Research Council of Canada (NSERC)
- Deutsche Forschungsgerneinschaft (DFG) [We 1801/2-4, GRK1302, SFB 685]
- German Federal Ministry of Education, Science, Research and Technology (Hep-Net)
- IZKF-Tubingen [Fo. 01KS9602]
- Wilhelm Sander-Stiftung
- Landesforschungsschwerpunktprogramm of the Ministry of Science, Research and Arts of the Land Baden-Wuerttemberg
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Rapid advances in the cancer stem cell (CSC) field have provided cause for optimism for the development of more reliable cancer therapies in the future. Strategies aimed at efficient targeting of CSCs are becoming important for monitoring the progress of cancer therapy and for evaluating new therapeutic approaches. Here, we characterize and compare the specific markers that have been found to be present on stem cells, cancer cells and CSCs in selected tissues (colon, breast, liver, pancreas and prostate). We then discuss future directions of this intriguing new research field in the context of new diagnostic and therapeutic opportunities.
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