Journal
TRENDS IN MICROBIOLOGY
Volume 27, Issue 1, Pages 17-25Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2018.08.009
Keywords
-
Categories
Funding
- ERC grant Microbes Inside [250172]
- Spinoza Award
- Soehngen Institute of Anaerobic Microbiology (SIAM) - Netherlands Organization for Scientific Research (NWO) [024.002.002]
- Marie Sklodowska-Curie fellowship of the European Union's Horizon 2020 research and innovation programme [703577]
- NWO Veni project [016.Veni.181.092]
- Soehngen
Ask authors/readers for more resources
Bacterial communities are known to impact human health and disease. Mixed species biofilms, mostly pathogenic in nature, have been observed in dental and gastric infections as well as in intestinal diseases, chronic gut wounds and colon cancer. Apart from the appendix, the presence of thick polymicrobial biofilms in the healthy gut mucosa is still debated. Polymicrobial biofilms containing potential pathogens appear to be an early-warning signal of developing disease and can be regarded as a tipping point between a healthy and a diseased state of the gut mucosa. Key biofilm-forming pathogens and associated molecules hold promise as biomarkers. Criteria to distinguish microcolonies from biofilms are crucial to provide clarity when reporting biofilm-related phenomena in health and disease in the gut.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available