Journal
TRENDS IN MICROBIOLOGY
Volume 22, Issue 3, Pages 120-127Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2014.01.001
Keywords
HIV; fungal infection; immunity; AIDS; mycoses
Categories
Funding
- Welcome Trust
- MRC
- MRC [G0902260] Funding Source: UKRI
- Medical Research Council [G0902260] Funding Source: researchfish
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Invasive fungal infections (IFIs) are a major cause of HIV-related mortality globally. Despite widespread rollout of combined antiretroviral therapy, there are still up to 1 million deaths annually from IFIs, accounting for 50% of all AIDS-related death. A historic failure to focus efforts on the IFIs that kill so many HIV patients has led to fundamental flaws in the management of advanced HIV infection. This review, based on the EMBO AIDS-Related Mycoses Workshop in Cape Town in July 2013, summarizes the current state of the-art in AIDS-related mycoses, and the key action points required to improve outcomes from these devastating infections.
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