Journal
TRENDS IN MICROBIOLOGY
Volume 22, Issue 6, Pages 304-306Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2014.04.011
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Two type VI secreted phospholipases D of Pseudomonas aeruginosa were identified as trans-kingdom virulence effectors, targeting both prokaryotic and eukaryotic host cells. Each of them triggers killing bacterial competitors and internalization into non-phagocytic cells. These type VI lipolytic enzymes are widely distributed among pathogens and may constitute a conserved strategy.
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