Journal
TRENDS IN MICROBIOLOGY
Volume 21, Issue 9, Pages 451-456Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2013.06.009
Keywords
autophagy; xenophagy; intracellular bacteria
Categories
Funding
- National Institutes of Health [AI041699, AI048770]
Ask authors/readers for more resources
Autophagy is an important membrane transport pathway that is conserved among eukaryotic cells. Although first described as an intracellular catabolic pathway used to break down self-components, autophagy has been found to play an important role in the elimination of intracellular pathogens. A variety of host mechanisms exist for recognizing and targeting intracellular bacteria to autophagosomes. Several intracellular bacteria have evolved ways to manipulate, inhibit, or avoid autophagy in order to survive in the cell. Thus, the autophagy pathway can be viewed as an evolutionarily conserved host response to infection.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available