Journal
TRENDS IN MICROBIOLOGY
Volume 20, Issue 4, Pages 192-198Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2012.01.006
Keywords
Staphylococcus aureus; evolution; host adaptation; human; livestock
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Funding
- BBSRC
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Staphylococcus aureus is a major pathogen responsible for severe nosocomial and community-associated infections of humans and infections of economically important livestock species. In recent years, studies into livestock-associated S. aureus including methicillin-resistant (MRSA) strains have provided new information regarding their origin and host adaptation, and their capacity to cause zoonotic infections of humans. Furthermore, a potential role for human activities such as domestication and industrialisation in the emergence of S. aureus clones affecting livestock has been highlighted. Here, I summarise recent developments in this emerging field and suggest questions of importance for future research efforts.
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