Journal
TRENDS IN MICROBIOLOGY
Volume 19, Issue 10, Pages 501-508Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2011.07.003
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Funding
- MRC [G0501453] Funding Source: UKRI
- Medical Research Council [G0501453] Funding Source: Medline
- Medical Research Council [G0501453] Funding Source: researchfish
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Novel high-throughput technologies such as yeast two-hybrid and RNA interference (RNAi) screens provide the tools to study interactions between viral proteins and the host on a genomic scale. In this review, we provide an overview of studies in which these technologies were applied and cif computational approaches for the analysis of the identified viral interactors in the context of the host cell. The results of these studies illustrate the advantages cif integrative systems biology approaches in the investigation of viral pathogens.
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