Journal
TRENDS IN IMMUNOLOGY
Volume 35, Issue 6, Pages 270-277Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.it.2014.04.003
Keywords
intestine; dendritic cells; macrophages; mouse
Categories
Funding
- Medical Research Council [MR/K021095/1] Funding Source: Medline
- Medical Research Council [MR/K021095/1] Funding Source: researchfish
- MRC [MR/K021095/1] Funding Source: UKRI
Ask authors/readers for more resources
Mononuclear phagocytes (MPs) in the murine intestine, comprising dendritic cells (DCs) and macrophages (M phi s), perform disparate yet complementary immunological functions. Functional analyses of these distinct MP subsets have been complicated by the substantial overlap in their surface phenotypes. Here, we review recent findings that have enabled more accurate definition of these MP subsets. We discuss these recent advances in the context of the current understanding of the functions of DCs and M phi s in the maintenance of intestinal homeostasis, and how their functions may alter when homeostasis is disrupted.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available