Journal
TRENDS IN IMMUNOLOGY
Volume 35, Issue 4, Pages 139-140Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.it.2014.02.005
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Microglia, the brain resident macrophages, are first responders to any violation of central nervous system (CNS) homeostasis. A recent paper in Cell shows that the specific depletion of microglia causes deficits in learning-induced synaptic remodeling through paucity of the microglial neurotrophin brain-derived neurotrophic factor (BDNF).
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