Journal
TRENDS IN GENETICS
Volume 24, Issue 3, Pages 124-132Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tig.2007.12.003
Keywords
-
Categories
Funding
- BBSRC [BB/F014082/1] Funding Source: UKRI
- NERC [NE/D012058/1] Funding Source: UKRI
- Natural Environment Research Council [NE/D012058/1] Funding Source: researchfish
- Biotechnology and Biological Sciences Research Council [BB/F014082/1] Funding Source: Medline
- Howard Hughes Medical Institute Funding Source: Medline
Ask authors/readers for more resources
The dissection of the circadian clock into its molecular components represents the most striking and well-studied example of a gene regulatory network underlying a complex behavioural trait. By contrast, the evolutionary analysis of the clock has developed more slowly. Here we review studies that have surveyed intraspecific clock gene variation over large geographical areas and have discovered latitudinal clines in gene frequencies. Such spatial patterns traditionally suggest that natural selection shapes genetic variation, but it is equally possible that population history, or a mixture of demography and selection, could contribute to the clines. We discuss how population genetics, together with functional assays, can illuminate these possible cases of natural selection in Drosophila clock genes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available