Journal
TRENDS IN COGNITIVE SCIENCES
Volume 15, Issue 2, Pages 85-93Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tics.2010.11.004
Keywords
-
Funding
- NIH [P30MH089888, R01MH091860]
- Sierra-Pacific Mental Illness Research Education and Clinical Center at the Palo Alto VA Health Care System
Ask authors/readers for more resources
Negative emotional stimuli activate a broad network of brain regions, including the medial prefrontal (mPFC) and anterior cingulate (ACC) cortices. An early influential view dichotomized these regions into dorsal-caudal cognitive and ventral-rostral affective subdivisions. In this review, we examine a wealth of recent research on negative emotions in animals and humans, using the example of fear or anxiety, and conclude that, contrary to the traditional dichotomy, both subdivisions make key contributions to emotional processing. Specifically, dorsal-caudal regions of the ACC and mPFC are involved in appraisal and expression of negative emotion, whereas ventral-rostral portions of the ACC and mPFC have a regulatory role with respect to limbic regions involved in generating emotional responses. Moreover, this new framework is broadly consistent with emerging data on other negative and positive emotions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available