Journal
TRENDS IN CELL BIOLOGY
Volume 22, Issue 11, Pages 555-556Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2012.08.008
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Funding
- NCI NIH HHS [R01 CA169291] Funding Source: Medline
- NIAID NIH HHS [R01 AI047891, R01 AI040646, R01 AI044828] Funding Source: Medline
- NIGMS NIH HHS [R01 GM096208, R37 GM052735] Funding Source: Medline
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Cells die by various mechanisms, only some of which have been elucidated in detail. Numerous 'active' forms of cell death exist in which the cell participates in its own death, including apoptosis, programmed necrosis, mitotic catastrophe, and the recently described ferroptosis. Here, we attempt to explain why there are so many different forms of cell death, and propose a distinction, between active death that constitutes 'suicide' versus 'sabotage'.
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