Journal
TRENDS IN CELL BIOLOGY
Volume 20, Issue 8, Pages 470-481Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2010.05.003
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Funding
- Leverhulme Trust [F/00094/BA - JC]
- Medical Research Council (MRC) [G0900109/90687 - RT]
- MRC [G0900109] Funding Source: UKRI
- Medical Research Council [G0900109] Funding Source: researchfish
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Armadillo (ARK-repeat proteins form a large family with diverse and fundamental functions in many eukaryotes. ARM-repeat proteins have largely been characterised in multicellular organisms and much is known about how a subset of these proteins function. The structure of ARM-repeats allows proteins containing them to be functionally very versatile. Are the ARM-repeat proteins in 'little creatures' as multifunctional as their better-studied relatives? The time is now right to start analysing ARM-repeat proteins in these new systems to better understand their cell biology. Here, we review recent advances in understanding the many cellular roles of both well-known and novel ARM-repeat proteins.
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