Journal
TRENDS IN CELL BIOLOGY
Volume 18, Issue 11, Pages 517-520Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2008.08.004
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Funding
- NIH
- National Cancer Institute
- DHHS [T32-CA09151]
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Some epithelia contain cells with multiple motile cilia that beat in a concerted manner. New tools and experimental systems have facilitated molecular studies of cilium biogenesis and the coordinated planar polarization of cilia that leads to their concerted motility. A recent elegant study using embryonic frog epidermis demonstrates that Dishevelled, a key regulator of both the Wnt-beta-catenin and planar cell polarity pathways, controls both the docking and planar polarization of ciliary basal bodies.
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