Journal
TRENDS IN CARDIOVASCULAR MEDICINE
Volume 18, Issue 5, Pages 157-162Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcm.2008.04.003
Keywords
-
Categories
Ask authors/readers for more resources
Coronary artery disease is a major socioeconomic problem in industrialized as well as in developing countries. Thus, many research efforts continue to address the identification of acquired and inherited risk factors of this complex disease. Recent advances in genotyping technology have made available newer and more powerful tools I-or the identification of susceptibility genes that in turn may provide new opportunities to evaluate the individual cardiovascular risk profile, detect novel disease pathways, and develop innovative therapeutic approaches. Replication of results is essential to establish unequivocally the impact of genetic variants in complex diseases. At the moment, only distinct but tightly linked single nucleotide polymorphisms on chromosome 9 have been consistently shown to be associated with different clinical phenotypes of coronary artery disease. (Trends Cardiovasc Med 2 008; IS: 157-162) (C) 2008, Elsevier Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available