Journal
TRENDS IN BIOTECHNOLOGY
Volume 29, Issue 12, Pages 595-600Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2011.06.008
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Funding
- MICROPHYTE [PTDC/EBB/102728/2008]
- Programa Operacional de Ciencia, Tecnologia e Inovacao - POCI
- Fundo Social Europeu - FSE (Portugal)
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Molecular hydrogen (H-2) obtained from biological sources provides an alternative to bulk chemical processes that is moving towards large-scale, economical generation of clean fuel for automotive engines. This opinion article examines recent improvements in H-2 production by wild and mutant strains of Chlamydomonas reinhardtii the green microalga currently considered the best eukaryotic H-2 producer. Here, we review various aspects of genetic and metabolic engineering of C. reinhardtii, as well as of process engineering. Additionally, we lay out possible scenarios that would lead to more efficient research approaches in the near future, as part of a consistent strategy for sustainable biohydrogen supply.
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