Journal
TRENDS IN BIOTECHNOLOGY
Volume 26, Issue 8, Pages 442-449Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2008.04.006
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Funding
- NCI NIH HHS [CA119349] Funding Source: Medline
- NIBIB NIH HHS [EB003647] Funding Source: Medline
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Nucleic acid ligands, also known as aptamers, are a class of macromolecules that are being used in several novel nanobiornedical applications. Aptamers are characterized by high affinity and specificity for their target, a versatile selection process, ease of chemical synthesis and a small physical size, which collectively make them attractive molecules for targeting diseases or as therapeutics. These properties will enable aptanners to facilitate innovative new nanotechnologies with applications in medicine. In this review, we will highlight recent developments in using aptamers in nanotechnology solutions for treating and diagnosing disease.
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