4.5 Review

Ex-vivo lung perfusion

Journal

TRANSPLANT INTERNATIONAL
Volume 28, Issue 6, Pages 643-656

Publisher

WILEY
DOI: 10.1111/tri.12317

Keywords

ex vivo lung perfusion; lung assessment; lung conditioning; lung preservation; lung repair; lung transplantation

Funding

  1. Fund for Scientific Research-Flanders [G.3C04.99]
  2. Clinical Research Fund from the University Hospitals Leuven

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This review outlines the new and promising technique of ex vivo lung perfusion and its clinical potential to increase the number of transplantable lungs and to improve the early and late outcome after transplantation. The rationale, the experimental background, the technique and protocols, and available devices for ex vivo lung perfusion are discussed. The current clinical experience worldwide and ongoing clinical trials are reviewed.

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