Journal
TRANSPLANT INTERNATIONAL
Volume 28, Issue 6, Pages 677-689Publisher
WILEY
DOI: 10.1111/tri.12354
Keywords
hypothermic oxygenated machine perfusion; marginal livers; oxygen; protective mechanisms
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Funding
- Swiss National Science Foundation [32003B-140776/1]
- Swiss National Science Foundation (SNF) [32003B_140776] Funding Source: Swiss National Science Foundation (SNF)
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Machine liver perfusion has significantly evolved during the last ten years to optimize extended criteria liver grafts and to address the worldwide organ shortage. This review gives an overview on available ex vivo and in vivo data on hypothermic machine liver perfusion. We discuss also possible protective pathways and show most recent clinical applications of hypothermic machine liver perfusion in human.
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