Journal
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
Volume 103, Issue 12, Pages 1190-1194Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.trstmh.2009.05.012
Keywords
Ascaris lumbricoides; Hookworm; Trichuris trichiura; Diagnosis; FLOTAC; Kato-Katz
Funding
- Kommission fur Reisestipendien des SCNAT
- Commission for Research Partnerships with Developing Countries
- Emanuel Burckhardt Foundation
- Swiss National Science Foundation [PPOOB-102883, PPOOB-119129]
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There is a tendency to neglect diagnostic issues in the era of 'preventive chemotherapy' in human helminthiases. However, accurate diagnosis cannot be overemphasized for adequate patient management and monitoring of community-based control programmes. Implicit is a diagnostic dilemma: the more effective interventions are in reducing helminth egg excretion, the less sensitive direct parasitological tests become. Here, experiences gained thus far with the FLOTAC technique for diagnosing common soil-transmitted helminth infections are summarized. A single FLOTAC has higher sensitivity than multiple Kato-Katz thick smears in detecting low-intensity infections. Further validation of the FLOTAC technique in different epidemiological settings is warranted, including diagnosis of intestinal schistosomiasis and food-borne trematodiases. (C) 2009 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
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