Related references
Note: Only part of the references are listed.Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking
Shuai Chen et al.
CELL METABOLISM (2011)
Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle
Michale Bouskila et al.
CELL METABOLISM (2010)
Fat Cell-Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism
Anil Kumar et al.
DIABETES (2010)
TBC1D1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle
Ding An et al.
DIABETES (2010)
The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling
Junghwa Lim et al.
GENES & DEVELOPMENT (2010)
Kinetic Evidence for Unique Regulation of GLUT4 Trafficking by Insulin and AMP-activated Protein Kinase Activators in L6 Myotubes
Daniel J. Fazakerley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cluster Analysis of Insulin Action in Adipocytes Reveals a Key Role for Akt at the Plasma Membrane
Yvonne Ng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mass and Information Feedbacks through Receptor Endocytosis Govern Insulin Signaling as Revealed Using a Parameter-free Modeling Framework
Cecilia Brannmark et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A Novel Pleckstrin Homology Domain-containing Protein Enhances Insulin-stimulated Akt Phosphorylation and GLUT4 Translocation in Adipocytes
Qiong L. Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Global Phosphoproteomics Identifies a Major Role for AKT and 14-3-3 in Regulating EDC3
Mark Larance et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
Protein Tyrosine Kinase 6 Directly Phosphorylates AKT and Promotes AKT Activation in Response to Epidermal Growth Factor
Yu Zheng et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Identification of Three Distinct Functional Sites of Insulin-mediated GLUT4 Trafficking in Adipocytes Using Quantitative Single Molecule Imaging
Hideaki Fujita et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
CNK1 is a novel Akt interaction partner that promotes cell proliferation through the Akt-FoxO signalling axis
R. D. Fritz et al.
ONCOGENE (2010)
Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells
Yi Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle
Christian Pehmoller et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
DOC2B: A Novel Syntaxin-4 Binding Protein Mediating Insulin-Regulated GLUT4 Vesicle Fusion in Adipocytes
Naofumi Fukuda et al.
DIABETES (2009)
The F-BAR protein CIP4 promotes GLUT4 endocytosis through bidirectional interactions with N-WASp and Dynamin-2
Sean M. Hartig et al.
JOURNAL OF CELL SCIENCE (2009)
The molecular basis of insulin-stimulated glucose uptake: signalling, trafficking and potential drug targets
Sophie E. Leney et al.
JOURNAL OF ENDOCRINOLOGY (2009)
The Phosphotyrosine Interactome of the Insulin Receptor Family and Its Substrates IRS-1 and IRS-2
Stefan Hanke et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
Identification of a Distal GLUT4 Trafficking Event Controlled by Actin Polymerization
Jamie A. Lopez et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling
Eva Gonzalez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Experimental and computational tools useful for (re)construction of dynamic kinase-substrate networks
Chris Soon Heng Tan et al.
PROTEOMICS (2009)
Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic
Kei Sakamoto et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators
Shuai Chen et al.
BIOCHEMICAL JOURNAL (2008)
The endosomal protein Appl1 mediates akt substrate specificity and cell survival in vertebrate development
Annette Schenck et al.
CELL (2008)
CaMKII-Mediated Phosphorylation of the Myosin Motor Myolc Is Required for Insulin-Stimulated GLUT4 Translocation in Adipocytes
Ming Fai Yip et al.
CELL METABOLISM (2008)
Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes
Yvonne Ng et al.
CELL METABOLISM (2008)
IRS1-independent defects define major nodes of insulin resistance
Kyle L. Hoehn et al.
CELL METABOLISM (2008)
R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population
David Meyre et al.
HUMAN MOLECULAR GENETICS (2008)
The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2β
Jenna L. Jewell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
GLUT4 vesicle recruitment and fusion are differentially regulated by Rac, AS160, and Rab8A in muscle cells
Varinder K. Randhawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
α-actinin-4 is selectively required for insulin-induced GLUT4 translocation
Ilana Talior-Volodarsky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle
Eric B. Taylor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Dissection of the insulin signaling pathway via quantitative phosphoproteomics
Marcus Krueger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Clathrin-dependent and independent endocytosis of glucose transporter 4 (GLUT4) in myoblasts:: Regulation by mitochondrial uncoupling
Costin N. Antonescu et al.
TRAFFIC (2008)
Direct quantification of fusion rate reveals a distal role for AS160 in insulin-stimulated fusion of GLUT4 storage vesicles
Li Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity
Anil Kumar et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR
Kathryn M. Geraghty et al.
BIOCHEMICAL JOURNAL (2007)
Activation of RaIA is required for insulin-stimulated glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c
Xiao-Wei Chen et al.
DEVELOPMENTAL CELL (2007)
Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1
William G. Roach et al.
BIOCHEMICAL JOURNAL (2007)
Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo
Veronique Calleja et al.
PLOS BIOLOGY (2007)
Rab10, a target of the AS160 rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane
Hiroyuki Sano et al.
CELL METABOLISM (2007)
Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells
Shuhei Ishikura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
GLUT4 is internalized by a cholesterol-dependent nystatin-sensitive mechanism inhibited by insulin
Vincent Blot et al.
EMBO JOURNAL (2006)
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
Estela Jacinto et al.
CELL (2006)
Insulin signaling diverges into Akt-dependent and -independent signals to regulate the recruitment/docking and the fusion of GLUT4 vesicles to the plasma membrane
Eva Gonzalez et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160
Georg Ramm et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition
Steven Stone et al.
HUMAN MOLECULAR GENETICS (2006)
Temporal dynamics of tyrosine phosphorylation in insulin signaling
Katrin Schmelzle et al.
DIABETES (2006)
mTOR•RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes
RC Hresko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking
M Larance et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain
CP Mîinea et al.
BIOCHEMICAL JOURNAL (2005)
Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein
L Eguez et al.
CELL METABOLISM (2005)
Insulin signaling meets vesicle traffic of GLUT4 at a plasma-membrane-activated fusion step
F Koumanov et al.
CELL METABOLISM (2005)
PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle
LQ Dong et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Synip phosphorylation does not regulate insulin-stimulated GLUT4 translocation
H Sano et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
p115 interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation
T Hosaka et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles
E Yamada et al.
JOURNAL OF CELL BIOLOGY (2005)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes
O Karylowski et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling
L Jebailey et al.
MOLECULAR ENDOCRINOLOGY (2004)
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles
DC Berwick et al.
JOURNAL OF CELL SCIENCE (2004)
Insulin increases cell surface GLUT4 levels by dose dependently discharging GLUT4 into a cell surface recycling pathway
R Govers et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Insulin stimulation of GLUT4 exocytosis, but not its inhibition of endocytosis, is dependent on RabGAP AS160
A Zeigerer et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B
SS Bae et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking
JS Bogan et al.
NATURE (2003)
Intracellular segregation of phosphatidylinositol-3,4,5-trisphosphate by insulin-dependent actin remodeling in L6 skeletal muscle cells
N Patel et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Insulin-induced GLUT4 translocation involves protein kinase C-λ-mediated functional coupling between Rab4 and the motor protein kinesin
T Imamura et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Cdc42 is a rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes
I Usui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin
M Inoue et al.
NATURE (2003)
Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change
CC Milburn et al.
BIOCHEMICAL JOURNAL (2003)
Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c
A Bose et al.
NATURE (2002)
A mathematical model of metabolic insulin signaling pathways
AR Sedaghat et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation
M Frödin et al.
EMBO JOURNAL (2002)
High-resolution structure of the pleckstrin homology domain of protein kinase B/Akt bound to phosphatidylinositol (3,4,5)-trisphosphate
CC Thomas et al.
CURRENT BIOLOGY (2002)
A method to identify serine kinase substrates - Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain
S Kane et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulated transport of the glucose transporter glut4
NJ Bryant et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein
J Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Rab11 is associated with GLUT4-containing vesicles and redistributes in response to insulin
A Kessler et al.
DIABETOLOGIA (2000)
Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake
LM Fletcher et al.
BIOCHEMICAL JOURNAL (2000)
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
A Toker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
