Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 63, Issue -, Pages 104-112Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2014.08.005
Keywords
2D-LC; LC x LC; Comprehensive two-dimensional liquid chromatography (LC x LC); Food analysis; High-temperature-UHPLC (HT-UHPLC); HT-UHPLC; Polymer analysis; Two-dimensional liquid chromatography; (2D-LC); UHPLC; Ultra-high-pressure liquid chromatography (UHPLC)
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Comprehensive two-dimensional liquid chromatography (LC x LC) has significantly improved the separation power of LC for complex samples. Our review opens with theoretical considerations about online LC x LC in order to explain why ultra-high-pressure LC (UHPLC) and more specifically, hightemperature (HT)-UHPLC are very convenient in the second dimension. We present some recent applications involving UHPLC in LC x LC. They cover a wide range of analytical fields, such as food analysis, life sciences, bioenergy and polymers. (C) 2014 Elsevier B.V. All rights reserved.
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