Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 45, Issue -, Pages 233-247Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2012.10.015
Keywords
Biological macromolecule; Enzyme immobilization; Food contaminant; Functionalized magnetic material (FMM); Glycopeptide; Peptide; Phosphopeptide; Protein; Proteome; Sample preparation
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Funding
- National Key Basic Research Foundation of China [2013CB910702]
- National Natural Science Foundation of China [91017013, 31070327, 21205091]
- Natural Science Fund for Creative Research Groups [20921062]
- Fundamental Research Funds for the Central Universities [1104001, 203271204, 203274612]
- Natural Science Foundation of Hubei Province [2011CDB440]
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Functionalized magnetic materials (FMMs) have been widely used in analytical chemistry. For sample preparation, FMMs show many advantages including easy surface modification, easy operation and high extraction efficiency. In this review, we describe the recent advances in FMMs in sample preparation. We first discuss their synthesis and characterization. We then focus on their application to enrichment of biological macromolecules of the proteome and contaminants in foods. Finally, we outline the prospects for FMMs in sample preparation. (C) 2013 Elsevier Ltd. All rights reserved.
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