Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 46, Issue -, Pages 189-197Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2013.02.003
Keywords
Bioanalysis; H4IIE-luc bioassay; Persistent organic pollutant (POP); Polychlorinated dibenzo-p-dioxin (PCDD); Polychlorinated dibenzofuran (PCDF); Soil; South Africa; Stockholm Convention; Time-of-flight mass spectrometry (TOF-MS); Two-dimensional gas chromatography (GCxGC)
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Funding
- Water Research Commission (WRC) of South Africa [K5/1561]
- Research Council of Norway [UID 64489]
- National Science and Engineering Research Council of Canada [326415-07]
- Canada Foundation for Infrastructure
- program of High Level Foreign Experts [GDW20123200120]
- State Administration of Foreign Experts Affairs, the P.R. China
- Einstein Professor Program of the Chinese Academy of Sciences
- Canada Research Chair program
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We outline the experiences and the challenges of optimizing two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GCxGC-TOF-MS) in conjunction with the H4IIE-lac bio-assay for analyzing polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in the South African context. Investigating such alternative analytical methods can assist countries with developing economies to meet their obligations under the Stockholm Convention. (C) 2013 Elsevier Ltd. All rights reserved.
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