Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 38, Issue -, Pages 129-142Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2012.05.004
Keywords
Biomarker; Blood; Breast milk; Emerging pollutant; Flame retardant; Liquid chromatography with tandem mass spectrometry (LC-MS/MS); Musk fragrance; Perfluorinated compound; Personal-care product; Urine
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Funding
- Valencia's Ministry of Education through the BEST research grant
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Biomonitoring is a very useful tool for assessing human exposure to environmental pollutants. This review discusses recent methods for the quantitative measurement of biomarkers of exposure to different classes of chemicals used in personal-care products (e.g., musk fragrances, preservatives, UV filters, and insect repellents) and consumer products (e.g., organophosphate flame retardants, phthalate esters, perfluorinated compounds, and industrial phenols). The measurements are mainly taken in urine, blood, and breast milk. We also discuss the different procedures commonly used for sample-pretreatment, extraction, and clean up, and chromatographic techniques currently used to determine these compounds. Finally, we present data on the main biomarkers occurring in different human specimens. (c) 2012 Elsevier Ltd. All rights reserved.
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