4.7 Review

Fluorescent conjugated polymers for chemical and biochemical sensing

Journal

TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 30, Issue 9, Pages 1513-1525

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2011.04.017

Keywords

Biochemical sensing; Chemical sensing; Conjugated polymer; Conjugated polyelectrolyte; DNA sensing; Explosives sensing; Fluorescence; Fluorescence resonance energy transfer (FRET); Metal-ion sensing; Molecular wire effect

Funding

  1. Spanish Ministry of Education and Science [CTQ2006-02309]
  2. FEDER
  3. Asturias Government [BP07-061]

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This review deals with the emerging field of fluorescent conjugated polymers for the development of chemical and/or biochemical sensors. As a result of their amplified physical properties due to a molecular wire effect, these materials offer excellent characteristics to develop different sensing schemes (e.g., employing direct superquenching or relying on development of fluorescence-resonance-energy-transfer formats). The versatility of their synthesis procedures allows us to introduce the desired functional groups to achieve analytically useful interactions with analytes [e.g., from transition-metal ions to explosives, or even, in recent years, relevant biomolecules (e.g., proteins or DNA, where conformational changes play a decisive role in detection)]. (C) 2011 Elsevier Ltd. All rights reserved.

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