Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 30, Issue 7, Pages 1035-1041Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2011.02.014
Keywords
Antibiotic residue; Chromatographic determination; Gas chromatography; Honey; Liquid chromatography; Mass spectrometry; Multi-class residue method; Sample preparation; Screening test; Tandem mass spectrometry
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Honey produced by honeybees is a valuable food product. The presence of xenobiotics in honey may harm its quality and constitute a danger to human health. Antibiotics are commonly applied by beekeepers to eliminate disease among honeybees. Moreover, ubiquitous administration of antibiotics may cause bacteria to become resistant to many drugs and spread antibiotic-resistant strains of bacteria. Appropriate sample preparation and determination of antibiotics at very low concentrations in foodstuffs are real analytical challenges. This article reviews analytical methods used for determination of residues of different sorts of antibiotic in honey and other honeybee products. (C) 2011 Elsevier Ltd. All rights reserved.
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