Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 28, Issue 4, Pages 404-415Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2008.12.006
Keywords
Bioanalysis; Chemiluminescence immunoassay; Chemiluminescence marker; Clinical chemistry; Environmental analysis; Immunorecognition; Label; Pharmaceutical analysis; Solid-phase material; Toxicological analysis
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Funding
- CAS Major Scientific Research and Equipment Development Projects [YZ-0632]
- National Key Technology RD Program [200613AF071303-1-1]
- CAS Graduate Innovation Foundation [YXLW-3]
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Chemiluminescence immunoassay (CLIA) offers several potential advantages and has applications in clinical chemistry, bioanalysis and environmental analysis. This review covers recent developments and applications of CLIA in immunorecognition, CL markers and related techniques, and solid-phase materials. We describe automation, integration and miniaturization of CLIA. We evaluate different CLIA systems and give some pointers as to the likely directions of future developments. (C) 2009 Elsevier Ltd. All rights reserved.
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