Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 28, Issue 1, Pages 88-95Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2008.10.010
Keywords
Biocompatibility; Magical angle spinning; Nanoparticle; Nanotube; Nuclear magnetic resonance; Reaction monitoring; Solid phase; Structure confirmation; Structure elucidation; Surface chemistry
Categories
Funding
- Shandong University
- American Lebanese Syrian Associated Charities (ALSAC)
- St. Jude Children's Research Hospital
Ask authors/readers for more resources
The chemical nature of a nanoparticle surface determines its bioactivity and toxicity in vivo. Rational surface-chemistry modifications play a key role in modulating the toxicity of nanoparticles and applying nanotechnology to life sciences and medicine. However, there is a bottleneck in characterizing the organic molecules attached to the nanoparticle surface after such modifications. This review summarizes recent developments in analysis of surface chemistry of nanomaterials using various proton nuclear magnetic resonance spectroscopy (H-1 NMR) techniques. While these developments have had a substantial impact on nanoparticle-surface chemistry, more quantitative, flexible, and practical analytical techniques and strategies have still to be developed. (c) 2008 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available