Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 27, Issue 5, Pages 437-446Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2008.03.003
Keywords
acoustic wave; aptamer; aptasensor; electrochemistry; impedance; label-free; mass spectrometry; microcantilever; optical device; SPR; surface-plasmon resonance
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In spite of the impressive advances in aptasensing, the search for label-free devices for the detection of the aptamer-ligand interaction is still a challenge. This review highlights the advantages and the limitations of using label-free detection strategies and summarizes the state of the art in this field. (C) 2008 Elsevier Ltd. All rights reserved.
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