4.4 Article

ATDB 2.0: A database integrated toxin-ion channel interaction data

Journal

TOXICON
Volume 56, Issue 4, Pages 644-647

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.toxicon.2010.05.013

Keywords

Interaction network; Toxin; Ion channel; Toxin Ontology; Ion channel ontology

Funding

  1. National Natural Science Foundation of China [30770437]
  2. 973 Program [2010CB529800]

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We have developed an updated version of the Animal Toxin Database (ATDB 2.0) that provides a new bioinformatics resource for analyzing toxin-channel (T-C) interactions. Data on more than 54,000 T-C interactions, including 9193 high-confidence interactions, has been extracted, formatted and mapped to toxin and ion channel databases The interaction data can be accessed easily through a new network browser on the website at http.//protchem hunnu edu cn/toxin. This resource may be useful for sequence pattern recognition and prediction of the function of new toxins. (C) 2010 Elsevier Ltd All rights reserved

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