Related references
Note: Only part of the references are listed.Temporal Concordance Between Apical and Transcriptional Points of Departure for Chemical Risk Assessment
Russell S. Thomas et al.
TOXICOLOGICAL SCIENCES (2013)
Update on EPA's ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management
Robert Kavlock et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2012)
Prioritizing Chemicals and Data Requirements for Screening-Level Exposure and Risk Assessment
Jon A. Arnot et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2012)
Providing the Missing Link: the Exposure Science Ontology ExO
Carolyn J. Mattingly et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY (2012)
Reduction of misleading (false) positive results in mammalian cell genotoxicity assays. II. Importance of accurate toxicity measurement
Paul Fowler et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2012)
Integrating pathway-based transcriptomic data into quantitative chemical risk assessment: A five chemical case study
Russell S. Thomas et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2012)
The exposure data landscape for manufactured chemicals
Peter P. Egeghy et al.
SCIENCE OF THE TOTAL ENVIRONMENT (2012)
Use of pooled samples from the national health and nutrition examination survey
Samuel P. Caudill
STATISTICS IN MEDICINE (2012)
Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment
Barbara A. Wetmore et al.
TOXICOLOGICAL SCIENCES (2012)
A Comprehensive Statistical Analysis of Predicting In Vivo Hazard Using High-Throughput In Vitro Screening
Russell S. Thomas et al.
TOXICOLOGICAL SCIENCES (2012)
High-performance metabolic profiling of plasma from seven mammalian species for simultaneous environmental chemical surveillance and bioeffect monitoring
Youngja H. Park et al.
TOXICOLOGY (2012)
Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment
Richard S. Judson et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2011)
Consideration of dosimetry in evaluation of ToxCast™ data
Lesa L. Aylward et al.
JOURNAL OF APPLIED TOXICOLOGY (2011)
Risk assessment of combined exposure to multiple chemicals: A WHO/IPCS framework
M. E. (Bette) Meek et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2011)
Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments
Karen Blackburn et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2011)
QSARs for PBPK modelling of environmental contaminants
T. Peyret et al.
SAR AND QSAR IN ENVIRONMENTAL RESEARCH (2011)
Application of Transcriptional Benchmark Dose Values in Quantitative Cancer and Noncancer Risk Assessment
Russell S. Thomas et al.
TOXICOLOGICAL SCIENCES (2011)
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets
Thomas B. Knudsen et al.
TOXICOLOGY (2011)
A practical approach to detect unique metabolic patterns for personalized medicine
Jennifer M. Johnson et al.
ANALYST (2010)
Impact of Environmental Chemicals on Key Transcription Regulators and Correlation to Toxicity End Points within EPA's ToxCast Program
Matthew T. Martin et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2010)
PubChem as a public resource for drug discovery
Qingliang Li et al.
DRUG DISCOVERY TODAY (2010)
Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data
David M. Reif et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2010)
Characterizing populations of individuals using pooled samples
Samuel P. Caudill
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY (2010)
BIOKINETIC MODELING AND IN VITRO-IN VIVO EXTRAPOLATIONS
Bas J. Blaauboer
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2010)
XENOBIOTIC-METABOLIZING ENZYME AND TRANSPORTER GENE EXPRESSION IN PRIMARY CULTURES OF HUMAN HEPATOCYTES MODULATED BY TOXCAST CHEMICALS
Daniel M. Rotroff et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2010)
Enhanced metabolite identification with MSE and a semiautomated software for structural elucidation
Britta Bonn et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2010)
Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening
Daniel M. Rotroff et al.
TOXICOLOGICAL SCIENCES (2010)
The Vision of Toxicity Testing in the 21st Century: Moving from Discussion to Action
Melvin E. Andersen et al.
TOXICOLOGICAL SCIENCES (2010)
A unified algorithm for predicting partition coefficients for PBPK modeling of drugs and environmental chemicals
Thomas Peyret et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2010)
The Toxicity Data Landscape for Environmental Chemicals
Richard Judson et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2009)
Profiling Chemicals Based on Chronic Toxicity Results from the US EPA ToxRef Database
Matthew T. Martin et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2009)
Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the US EPA's ToxRefDB
Thomas B. Knudsen et al.
REPRODUCTIVE TOXICOLOGY (2009)
Profiling the Reproductive Toxicity of Chemicals from Multigeneration Studies in the Toxicity Reference Database
Matthew T. Martin et al.
TOXICOLOGICAL SCIENCES (2009)
Profiling Bioactivity of the ToxCast Chemical Library Using BioMAP Primary Human Cell Systems
Keith A. Houck et al.
JOURNAL OF BIOMOLECULAR SCREENING (2009)
IPCS framework for analyzing the relevance of a noncancer mode of action for humans
Alan R. Boobis et al.
CRITICAL REVIEWS IN TOXICOLOGY (2008)
Issues in consumer exposure modeling: Towards harmonization on a global scale
Stylianos Kephalopoulos et al.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY (2007)
Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling
Yu-Mei Tan et al.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY (2007)
A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure
Russell S. Thomas et al.
TOXICOLOGICAL SCIENCES (2007)
Screening of soil fungi for in vitro degradation of endosulfan
Sarfraz Hussain et al.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2007)
Mechanistic approaches to volume of distribution predictions: Understanding the processes
Trudy Rodgers et al.
PHARMACEUTICAL RESEARCH (2007)
Innovation - The Connectivity Map: a new tool for biomedical research
Justin Lamb
NATURE REVIEWS CANCER (2007)
IPCS framework for analyzing the relevance of a cancer mode of action for humans
Alan R. Boobis et al.
CRITICAL REVIEWS IN TOXICOLOGY (2006)
The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds
Martin Van den Berg et al.
TOXICOLOGICAL SCIENCES (2006)
Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions
Trudy Rodgers et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
Strategies to assess systemic exposure of chemicals in subehronic/chronic diet and drinking water studies
SA Saghir et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2006)
Physiologically based pharmacokinetic modeling 1: Predicting the tissue distribution of moderate-to-strong bases
T Rodgers et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution
P Poulin et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
High throughput physicochemical profiling for drug discovery
EH Kerns
JOURNAL OF PHARMACEUTICAL SCIENCES (2001)
Compendium of chemical carcinogens by target organ: Results of chronic bioassays in rats, mice, hamsters, dogs, and monkeys
LS Gold et al.
TOXICOLOGIC PATHOLOGY (2001)
IPCS conceptual framework for evaluating a mode of action for chemical carcinogenesis
C Sonich-Mullin et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2001)
Share Paper
