Journal
AUSTRALASIAN JOURNAL OF DERMATOLOGY
Volume 57, Issue 2, Pages 137-140Publisher
WILEY-BLACKWELL
DOI: 10.1111/ajd.12294
Keywords
adalimumab; anti-TNF-; biologics; drug survival; etanercept; infliximab; PASI; psoriasis; ustekinumab
Categories
Ask authors/readers for more resources
We evaluated and compared patients' long-term adherence to biological therapies in a real-life clinical setting. Secondary aims included weight changes on biological therapy and reporting adverse effects. This prospective case-note review included 58 patients, undergoing 84 treatment series including etanercept (21), adalimumab (24), infliximab (14) and ustekinumab (25). Patients' adherence was greatest with ustekinumab (being 6.7-fold less likely to withdraw from treatment than etanercept, P=0.014), while the difference in treatment adherence of adalimumab and infliximab compared to etanercept was not statistically significant. Adalimumab and infliximab were associated with an increase in weight, while ustekinumab was associated with weight loss compared with etanercept (not statistically significant). Long-term patient adherence to biologic therapy in patients with psoriasis is greatest with ustekinumab.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available