Journal
TISSUE ENGINEERING PART B-REVIEWS
Volume 16, Issue 4, Pages 405-412Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/ten.teb.2009.0714
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Funding
- Biotechnology and Biological Sciences Research Council (BBSRC) [BB/F013892/1]
- Biotechnology and Biological Sciences Research Council [BB/F013892/2, BB/F013892/1] Funding Source: researchfish
- BBSRC [BB/F013892/1, BB/F013892/2] Funding Source: UKRI
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Cell adhesion to scaffolds has remained one of the challenges in tissue engineering. Although protein surface modification has been proven to enhance cell adhesion and retention, its specificity depending on cell and biomaterial types means that the best protein and concentration must be established for each specific application. This review focuses on the improvement of cell adhesion for human mesenchymal stem cells with an osteogenesis approach. A brief outline of the cell adhesion process and extracellular matrix proteins precedes an overview of works focused on the adhesion of mesenchymal stem cells and osteoblasts to biomaterials and this effect in their differentiation into osteoblasts.
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