Journal
THROMBOSIS RESEARCH
Volume 125, Issue -, Pages S70-S73Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.thromres.2010.01.042
Keywords
Tissue factor; Cell type; Sepsis; Endotoxemia; Disseminated intravascular coagulation
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Funding
- National Institutes of Health and American Heart Association
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Sepsis is a systemic host response to infection by pathogenic microorganisms. Activation of the coagulation cascade during endotoxemia and sepsis leads to disseminated intravascular coagulation. This review focuses on tissue factor expression by hematopoietic and non-hematopoietic cells and its contribution to the activation of coagulation during endotoxemia and sepsis. (C) 2010 Elsevier Ltd. All rights reserved.
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