Journal
THORAX
Volume 70, Issue 2, Pages 181-181Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/thoraxjnl-2014-205958
Keywords
Sleep apnoea; Cytokine Biology
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Funding
- British Heart Foundation [PG/05/068/19057, PG/05/068] Funding Source: Medline
- Medical Research Council [MC_U122888468] Funding Source: Medline
- Department of Health [HCS/08/012, NIHR-HCS-P13-04-001] Funding Source: Medline
- MRC [MC_U122888468] Funding Source: UKRI
- Medical Research Council [MC_U122888468] Funding Source: researchfish
- National Institute for Health Research [NIHR-HCS-P13-04-001, HCS/08/012] Funding Source: researchfish
- National Institutes of Health Research (NIHR) [NIHR-HCS-P13-04-001, HCS/08/012] Funding Source: National Institutes of Health Research (NIHR)
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The Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular (MOSAIC) trial compared 6months of CPAP therapy, versus no CPAP, in 391 patients with minimally symptomatic obstructive sleep apnoea (OSA). We now report some exploratory outcomes, markers of systemic inflammation (interleukin 6 (IL-6), IL-10, C reactive protein, tumour necrosis factor). We found no consistent changes (all p values >0.13). Trial registration number: ISRCTN 34164388.
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