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Designs, formats and applications of lateral flow assay: A literature review

Journal

JOURNAL OF SAUDI CHEMICAL SOCIETY
Volume 19, Issue 6, Pages 689-705

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.jscs.2014.09.001

Keywords

Point of care testing; Lateral flow immunoassay; Dry reagent strip biosensor; Aptamer

Funding

  1. KFUPM
  2. King Abdul Aziz City for Science and Technology (KACST) through the Science and Technology Unit at King Fahd University of Petroleum & Minerals (KFUPM) as part of the National Science, Technology and Innovation Plan [09-BIO780-04]

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This manuscript provides a brief overview of latest research involving the use of lateral flow assay for qualitative and quantitative analysis in different areas. The excellent features and versatility of detection formats make these strips an ideal choice for point of care applications. We outline and critically discuss detection formats, molecular recognition probes, labels, and detection systems used in lateral flow assay. Applications in different fields along with selected examples from the literature have been included to show analytical performance of these devices. At the end, we summarize accomplishments, weaknesses and future challenges in the area of lateral flow strips. (C) 2014 King Saud University. Production and hosting by Elsevier B.V. All rights reserved.

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