Related references
Note: Only part of the references are listed.Pharmacological modulation of GITRL/GITR system: therapeutic perspectives
Giuseppe Nocentini et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Glucocorticoid-Induced Leucine Zipper (GILZ) Over-Expression in T Lymphocytes Inhibits Inflammation and Tissue Damage in Spinal Cord Injury
Emanuela Esposito et al.
NEUROTHERAPEUTICS (2012)
The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice
M. Galuppo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Dendritic cells engineered to express GITRL enhance therapeutic immunity in murine Lewis lung carcinoma
Jie Ma et al.
CANCER LETTERS (2011)
Association of functional GITR gene polymorphisms related to expression of glucocorticoid-induced tumour necrosis factor-receptor (GITR) molecules with prognosis of autoimmune thyroid disease
R. Tomizawa et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2011)
CD4+CD25lowGITR+ cells: A novel human CD4+ T-cell population with regulatory activity
Rodolfo Bianchini et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity
Simona Ronchetti et al.
IMMUNOLOGY LETTERS (2011)
Dual Roles of Immune Cells and Their Factors in Cancer Development and Progression
Brian F. Zamarron et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2011)
Stimulation of the Glucocorticoid-Induced TNF Receptor Family-Related Receptor on CD8 T Cells Induces Protective and High-Avidity T Cell Responses to Tumor-Specific Antigens
Anik L. Cote et al.
JOURNAL OF IMMUNOLOGY (2011)
GITR GENE DELETION AND GITR-FC SOLUBLE PROTEIN ADMINISTRATION INHIBIT MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN
Maria Galuppo et al.
SHOCK (2011)
Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation
Theresa Placke et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2010)
Two Distinct Mechanisms of Augmented Antitumor Activity by Modulation of Immunostimulatory/Inhibitory Signals
Jun Mitsui et al.
CLINICAL CANCER RESEARCH (2010)
CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection
Laura M. Snell et al.
JOURNAL OF IMMUNOLOGY (2010)
Tumor-specific Crosslinking of GITR as Costimulation for Immunotherapy
Tanja Burckhart et al.
JOURNAL OF IMMUNOTHERAPY (2010)
Stimulation of Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family-Related Protein Ligand (GITRL) Induces Inflammatory Activation of Microglia in Culture
Heehong Hwang et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
Agonist Anti-GITR Monoclonal Antibody Induces Melanoma Tumor Immunity in Mice by Altering Regulatory T Cell Stability and Intra-Tumor Accumulation
Adam D. Cohen et al.
PLOS ONE (2010)
Role of the Glucocorticoid-Induced TNFR-Related Protein (GITR)-GITR Ligand Pathway in Innate and Adaptive Immunity
Miyuki Azuma
CRITICAL REVIEWS IN IMMUNOLOGY (2010)
Identification of regulatory T Cells in systemic lupus erythematosus
Roberto Gerli et al.
AUTOIMMUNITY REVIEWS (2009)
Localized expression of GITR-L in the tumor microenvironment promotes CD8+ T cell dependent anti-tumor immunity
John S. Cho et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2009)
Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Protein Ligand Subverts Immunosurveillance of Acute Myeloid Leukemia in Humans
Tina Baessler et al.
CANCER RESEARCH (2009)
Glucocorticoid-induced tumor necrosis factor receptor stimulation enhances the multifunctionality of adoptively transferred tumor antigen-specific CD8+ T cells with tumor regression
Naoko Imai et al.
CANCER SCIENCE (2009)
Glucocorticoid-induced leucine zipper (GILZ): a new important mediator of glucocorticoid action
Emira Ayroldi et al.
FASEB JOURNAL (2009)
Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours
Jinhua Piao et al.
IMMUNOLOGY (2009)
GITR Triggering Induces Expansion of Both Effector and Regulatory CD4+ T Cells In Vivo
Ronald W. van Olffen et al.
JOURNAL OF IMMUNOLOGY (2009)
GITR ligand-costimulation activates effector and regulatory functions of CD4+ T cells
Hanna Igarashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Neutralization of tumor-derived soluble Glucocorticoid-Induced TNFR-Related Protein ligand increases NK cell anti-tumor reactivity
Katrin M. Baltz et al.
BLOOD (2008)
Regulatory T cell-resistant CD8+ T cells induced by glucocorticoid-induced tumor necrosis factor receptor signaling
Hiroyoshi Nishikawa et al.
CANCER RESEARCH (2008)
Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer
Peisheng Hu et al.
CLINICAL CANCER RESEARCH (2008)
Co-inhibitory roles for glucocorticoid-induced TNF receptor in CD1d-dependent natural killer T cells
Shuming Chen et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Glucocorticoid-induced tumor necrosis factor receptor negatively regulates activation of human primary natural killer (NK) cells by blocking proliferative signals and increasing NK cell apoptosis
Baoying Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
NGF-promoted axon growth and target innervation requires GITRL-GITR signaling
Gerard W. O'Keeffe et al.
NATURE NEUROSCIENCE (2008)
Pivotal roles of CD4+ effector T cells in mediating agonistic Anti-GITR mAb-induced-immune activation and tumor immunity in CT26 tumors
Pengfei Zhou et al.
JOURNAL OF IMMUNOLOGY (2007)
Glucocorticoid-induced TNFR-Related protein lowers the threshold of CD28 costimulation in CD8+ T cells
Simona Ronchetti et al.
JOURNAL OF IMMUNOLOGY (2007)
Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells
Sandra Tuyaerts et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis
E. Bae et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
GITR modulates innate and adaptive mucosal immunity during the development of experimental colitis in mice
L. Santucci et al.
GUT (2007)
Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation
Salvatore Cuzzocrea et al.
FASEB JOURNAL (2007)
GITR-GITRL system, a novel player in shock and inflammation
Ludovic Tibor Krausz et al.
THESCIENTIFICWORLDJOURNAL (2007)
Glucocorticoid-induced tumour necrosis factor receptor family-related receptor signalling exacerbates hapten-induced colitis by CD4+ T cells
Sun K. Lee et al.
IMMUNOLOGY (2006)
Soluble glucocorticoid-induced tumor necrosis factor receptor stimulates osteoclastogenesis by down-regulation of osteoprotegerin in bone marrow stromal cells
Hyun-Hee Shin et al.
BONE (2006)
The GITR-GITRL interaction: co-stimulation or contrasuppression of regulatory activity?
Ethan M. Shevach et al.
NATURE REVIEWS IMMUNOLOGY (2006)
Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation
Salvatore Cuzzocrea et al.
JOURNAL OF IMMUNOLOGY (2006)
Conversion of alloantigen-specific CD8+ T cell anergy to CD8+ T cell priming through in vivo ligation of glucocorticoid-induced TNF receptor
Juyang Kim et al.
JOURNAL OF IMMUNOLOGY (2006)
Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL)
S Hanabuchi et al.
BLOOD (2006)
Agonist anti-GITR antibody enhances vaccine-induced CD8+ T-cell responses and tumor immunity
AD Cohen et al.
CANCER RESEARCH (2006)
Engagement of glucocorticoid-induced TNF receptor costimulates NKT cell activation in vitro and in vivo
Hyun Jung Kim et al.
JOURNAL OF IMMUNOLOGY (2006)
Interference with CD4+ CD25+ T-cell-mediated tolerance to experimental autoimmune thyroiditis by glucocorticoid-induced tumor necrosis factor receptor monoclonal antibody
GP Morris et al.
JOURNAL OF AUTOIMMUNITY (2006)
Glucocorticoid-induced tumour necrosis factor receptor (GITR) and its ligand (GITRL) in atopic dermatitis
Jane Baumgartner-Nielsen et al.
ACTA DERMATO-VENEREOLOGICA (2006)
Glucocorticoid-induced tumor necrosis factor receptor is a p21Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosis
J Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The glucocorticoid-induced tumor necrosis factor receptor-related gene modulates the response to Candida albicans infection
M Agostini et al.
INFECTION AND IMMUNITY (2005)
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells
K Ko et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology
S Suvas et al.
JOURNAL OF VIROLOGY (2005)
Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis
S Cuzzocrea et al.
FASEB JOURNAL (2005)
In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1
S La et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2005)
Glucocorticoid-induced TNF receptor functions as a costimulatory receptor that promotes survival in early phases of T cell activation
EM Esparza et al.
JOURNAL OF IMMUNOLOGY (2005)
Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-κB ligand (RANKL) in osteoclast cells
HH Shin et al.
BONE (2005)
Bypassing tumor-associated immune suppression with recombinant adenovirus constructs expressing membrane bound or secreted GITR-L
B Calmels et al.
CANCER GENE THERAPY (2005)
Cutting edge:: Ligation of the glucocorticoid-induced TNF receptor enhances autoreactive CD4+ T cell activation and experimental autoimmune encephalomyelitis
AP Kohm et al.
JOURNAL OF IMMUNOLOGY (2004)
GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations
S Ronchetti et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
Functional impairment of CD8+ T cells by regulatory T cells during persistent retroviral infection
U Dittmer et al.
IMMUNITY (2004)
TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death
YF Zhan et al.
INTERNATIONAL IMMUNOLOGY (2004)
GITR activation induces an opposite effect on alloreactive CD4+ and CD8+ T cells in graft-versus-host disease
SJ Muriglan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells
F Kanamaru et al.
JOURNAL OF IMMUNOLOGY (2004)
Overlap between molecular markers expressed by naturally occurring CD4+CD25+ regulatory T cells and antigen specific CD4+CD25+ and CD8+CD28- T suppressor cells
L Scotto et al.
HUMAN IMMUNOLOGY (2004)
Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock
S Cuzzocrea et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+ CD25+ T cells
GL Stephens et al.
JOURNAL OF IMMUNOLOGY (2004)
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells
M Tone et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Stimulation of CD25+CD4+regulatory T cells through GITR breaks immunological self-tolerance
J Shimizu et al.
NATURE IMMUNOLOGY (2002)
CD4+CD25+ immunoregulatory T cells:: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
RS McHugh et al.
IMMUNITY (2002)
Identification of three novel mRNA splice variants of GITR
G Nocentini et al.
CELL DEATH AND DIFFERENTIATION (2000)
Share Paper
