Journal
SCIENTIFIC WORLD JOURNAL
Volume -, Issue -, Pages 1-7Publisher
HINDAWI PUBLISHING CORPORATION
DOI: 10.1100/2012/619080
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Funding
- VIT University
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The diversified bis-isoquinolinones were obtained in two steps, utilizing homophthalic acid and various acid chlorides providing 3-substituted isocoumarins in the first step which on further condensation with 1,7-heptadiamine involving C-N bond formation from the lactone in the presence of 10mol% zinc oxide nanoparticles (ZnO NPs) (<150 nm) afforded the desired bis-isoquinolinones in high yield and purity. The synthesized compounds were then characterized using FTIR, H-1 NMR, C-13 NMR, and HRMS techniques.
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