Journal
TETRAHEDRON-ASYMMETRY
Volume 24, Issue 4, Pages 212-216Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2013.01.012
Keywords
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Funding
- European Union within the European Regional Development Fund [POIG.01.01.02-14-102/09]
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Optically active 3-alkyl-3-hydroxymethy1-5-vinyltetrahydrofurans were synthesised from the corresponding methyl or isobutyl carbonates of omega,omega-bis(hydroxymethyl)-alpha,beta-unsaturated alcohols via palladium-catalysed cyclisation. The use of chiral ligands gave the corresponding tetrahydrofuran derivatives, which had er values that ranged from moderate to good. (C) 2013 Elsevier Ltd. All rights reserved.
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