Journal
TETRAHEDRON-ASYMMETRY
Volume 23, Issue 5, Pages 381-387Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2012.03.002
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Funding
- UGC, New Delhi
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The stereoselective synthesis towards biologically active verbalactone and (+)-(3R,5R)-3-hydroxy-5-decanolide has been described. The key functionalities are derived from a chiral-auxiliary mediated acetate aldol addition, an oxa-Michael reaction and a 1,3-syn-reduction. (C) 2012 Elsevier Ltd. All rights reserved.
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