Journal
TETRAHEDRON-ASYMMETRY
Volume 22, Issue 11, Pages 1231-1233Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2011.06.024
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A biomimetic, inexpensive, and simple method for the stereoselective thio-Michael addition of thiols to chalcones has been developed using bovine serum albumin (BSA) as a catalyst. Optically active products are obtained in high yield and with enantiomeric excesses of up to 70%. (C) 2011 Elsevier Ltd. All rights reserved.
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